Image

Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy Volunteers

Testing KarXT's safety with anti-nausea meds in healthy people.

Recruiting
18-65 years
All
Phase 4

This study checks if taking KarXT, a medicine for mental health issues like schizophrenia, with anti-nausea drugs helps reduce feeling sick and throwing up. KarXT can make your stomach upset, especially at first. The study is for healthy people who will try taking KarXT with medicine that helps stop nausea, either regularly or when needed. The aim is to find out which way works best and is safest.

Key Points:

  • 3-week stay: Participants must stay at the study place for 3 weeks.
  • Eligibility: You must be healthy with no major illnesses and willing to follow study rules.
  • Risks: People with certain health conditions cannot join. Discuss with a doctor to see if you qualify.

This study will help doctors figure out how to make starting KarXT easier for patients by managing side effects better.

Study details
    Healthy Volunteers

NCT07681076

Karuna Therapeutics, Inc., a Bristol Myers Squibb company

19 September 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race*
Are you a healthy volunteer
Ethnicity*
Are you a healthy volunteer
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.