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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Join a study on heart failure and obesity treatments.

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18 years and older
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Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at how well a new medicine, NNC0487-0111, works for people with heart failure and obesity. Heart failure is when the heart doesn't pump blood as well as it should. Obesity means having too much body weight. The study will compare NNC0487-0111 to a placebo (a harmless pill with no medicine) to see if it helps people feel better. People in the study will get a shot once a week. They will get either the new medicine or the placebo by chance, like flipping a coin. NNC0487-0111 is a new medicine that doctors don’t prescribe yet, but it has been tested in people before.

  • Participants must have a BMI of 30 or more.
  • People with certain heart or lung conditions cannot join.
  • Eligible participants may need to visit the study site regularly.
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Study details
    Obesity
    Heart Failure

NCT07567001

Novo Nordisk A/S

18 July 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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