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A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

Exploring Aticaprant for schizophrenia safety and tolerability.

Recruiting
18-55 years
All
Phase 1

This study is checking how safe and comfortable a drug called aticaprant is for people with schizophrenia, a mental illness causing thoughts and feelings to be different. The study compares aticaprant with a placebo (a fake pill) to see if it's better. People can join if they're already stable on one type of medicine for schizophrenia and are seeing a doctor regularly. They shouldn't change other medicines like antidepressants for at least 8 weeks before joining. Some people can't join if they have other mental disorders, recent substance issues, or certain stomach problems. The study involves taking medicine and attending visits.

  • Study involves taking medication and attending regular check-ups.
  • Participants should be stable on their current schizophrenia medication.
  • Some mental health or substance issues might exclude you from participating.
Study details
    Schizophrenia

NCT07615426

Janssen Research & Development, LLC

6 June 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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