Study Description: This research looks into how different risk factors, such as a person's age, gender, other health issues, and the type of cancer treatment called immunotherapy, affect the chances of getting side effects from the medication. Immunotherapy helps the body's immune system fight cancer. The aim is to help doctors choose better treatments in the future.

Key Points:

• The study lasts for 12 months, involving questionnaires at different times.
• Participants need to provide a tissue sample and may opt to give blood samples.
• No chemotherapy or other therapies should be received with the ICI-based therapy.

Eligibility: Participants must be 18 years or older, planning to receive immunotherapy (ICI-based therapy) for solid tumors, and should not have had certain treatments recently. They must complete assessments in English, Spanish, or French.

Note: Participants need an electronic device for answering surveys if choosing the electronic method. Consent is required, and the study is investigational, meaning it’s still being tested.