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Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

Comparing two ways of giving Frexalimab for multiple sclerosis treatment.

Recruiting
18-60 years
All
Phase 3

This study compares two ways of giving a medicine called Frexalimab to adults with Multiple Sclerosis (MS). MS is a disease where the body's defense system attacks the brain and spinal cord by mistake. Frexalimab can be given either under the skin (subcutaneous or SC) or into a vein (intravenous or IV). People aged 18 to 60 who have certain types of MS are invited to join. The study lasts for 48 weeks (about a year) and may continue longer for optional safety checks.

  • The study requires 11 to 17 visits depending on the method of administration.
  • Participants must not have other health issues that could confuse the study results.
  • Both men and women should follow certain rules about preventing pregnancy during the study.

Consider joining if you have Relapsing MS (RMS) or non-relapsing Secondary Progressive MS (nrSPMS) and meet the study rules. There will be health checks to see if you qualify, and safety is a priority throughout the study.

Study details
    Multiple Sclerosis

NCT07325292

Sanofi

6 June 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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