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A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

Study on ABBV-438 for side effects and disease changes in myeloma.

Recruiting
18 years and older
All
Phase 1

Multiple Myeloma (MM) is a disease affecting certain blood cells in the bone. This study tests a new drug called **ABBV-438** for adults with MM that has returned or isn't responding to treatment. The drug is given through an **intravenous (IV)** line, which means it's delivered directly into your vein.

The study has two parts: Part 1 finds the best dose, and Part 2 confirms it. About 127 adults worldwide will join, with each getting ABBV-438 in multiple doses. The study lasts about 69.5 months, and participants will need to visit a hospital or clinic regularly. Doctors will check your health through different tests like blood work and questionnaires.

  • Study length is nearly 70 months with regular hospital visits.
  • Participants will receive medication through an IV.
  • Higher treatment burden may occur compared to regular treatment.
Study details
    Multiple Myeloma

NCT07409246

AbbVie

25 April 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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