The **PREDICT Registry** is a study to observe how doctors decide on treatments for patients with a breast condition called **DCIS** (Ductal Carcinoma In Situ). DCIS is a type of breast cancer that hasn't spread. **DCISionRT** is a test that helps doctors understand the risk level of DCIS and guide treatment decisions. The study involves collecting tissue samples and details from patients who have had this test. The information is stored safely without personal details. Key Points: - The study could last up to 10 years with regular follow-up. - It involves up to 3,000 participants from the U.S. - Participants need a DCISionRT test and should be capable of receiving certain treatments. Participants can be between 30-85 years old and must have had DCIS diagnosed within 120 days. Those with certain conditions, like invasive cancer, or previous related treatments, might not be eligible. This study helps understand how DCISionRT results influence treatment plans.