**Study Summary:** This study is testing two **experimental drugs** called **ALN-ANG3** and **evinacumab**. These drugs are for people with **diabetic kidney disease**. This condition happens when diabetes damages the kidneys over time. The study wants to see if the drugs are safe and work well. Researchers will also check for any **side effects** and how much of the drug is present in the blood at different times. **Key Points:** - The study requires participants with **type 2 diabetes** and specific kidney function levels. - If you have a history of non-diabetic kidney disease or have needed dialysis, you cannot participate. - Participants will be monitored for safety and drug levels in their blood. People can join if they have **type 2 diabetes** and specific blood and urine test results. They cannot join if they have other serious kidney issues or have been in the hospital recently. Participants should be stable, not needing emergency care. The study will help understand if these new drugs can help people with diabetic kidney disease. **Note:** Other rules may apply for joining the study.