This study aims to test a new drug, LHP588, for people with mild to moderate Alzheimer's disease (AD) and a specific gum infection called P. gingivalis, which may be linked to dementia. The drug is tested to see if it can slow down the worsening of AD symptoms. To find out if you have the infection, a simple saliva test is done. Participants will take a capsule once a day, but neither they nor the doctor will know if it’s the actual drug or a placebo (a look-alike pill with no active ingredients). The study lasts up to 64 weeks, including screening and follow-up periods. Caregivers must participate, and there will be about 20 visits to the study center. Participants might also receive phone calls from the doctor.
- Duration: Up to 64 weeks with 20+ visits
- Participation: Caregiver involvement required
- Procedure: Daily capsule, saliva, and blood tests
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