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Opioid-Sparing Joint Replacement

Exploring joint replacements with less reliance on opioids.

Recruiting
18 years and older
All
Phase 3

This study is about finding ways to reduce the use of opioids, which are strong painkillers, after hip replacement surgery for osteoarthritis. Osteoarthritis is a condition where the joints become painful and stiff. The trial tests if a plan using fewer opioids can still control pain well. Some people will receive a regular opioid prescription, while others get a placebo, which is a tablet with no medicine in it. Everyone will have access to a small amount of a strong pain reliever, hydromorphone, if needed.

The study checks how much opioids are used, pain levels, and how patients feel about their treatment in the first week, and then again at 3 weeks and 3 months after surgery. The study helps see if using fewer opioids still offers good pain relief and patient satisfaction without increasing risks.

  • This study involves follow-up visits at 1 week, 3 weeks, and 3 months.
  • Eligibility requires no opioid use 4 weeks before surgery and ability to attend follow-ups.
  • Participants receive counseling from a Life Care Specialist and may be given a placebo.
Study details
    Pain Management
    Opioid Consumption

NCT07348627

Emory University

25 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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