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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

Join a study to help prevent heart and kidney issues in diabetes.

Recruiting
40-80 years
All
Phase 4

This study, called PRECIDENTD, looks at two treatments for people with type 2 diabetes (T2D) and heart or kidney disease risks. **Type 2 diabetes** means your body can't use sugar properly. **Atherosclerotic cardiovascular disease (ASCVD)** is when arteries harden, leading to heart issues. The study will test two medications: **SGLT2 inhibitors** and **GLP-1 receptor agonists.** Both help control blood sugar. The study will see which treatment helps better with heart attacks, strokes, and kidney problems.

Participants must have T2D and be at risk for heart disease. If you have problems like past heart attacks, strokes, or artery issues, you may qualify. You need to be okay with being assigned to one of the two medications and have your health monitored until the study ends.

  • The study involves 6,000 participants, following them for several years.
  • Participants will need to take medication and attend regular health checks.
  • It's important to have insurance that covers the study medications.
Study details
    Type2Diabetes
    ASCVD

NCT05390892

Brigham and Women's Hospital

25 April 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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