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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

Testing Icovamenib for Type 2 Diabetes patients not meeting glucose goals.

Recruiting
18-70 years
All
Phase 2

This study tests a medicine called icovamenib for adults with Type 2 Diabetes (T2D) who are using Ozempic but still have high blood sugar. The trial lasts for 52 weeks, just over a year. Participants will either receive icovamenib or a placebo (a harmless pill that doesn't affect your body) alongside their Ozempic treatment.

The main aim is to see if icovamenib helps lower blood sugar levels more effectively than just Ozempic alone. The study is double-blind, meaning neither the doctors nor the participants know who is receiving the actual medicine, which helps ensure unbiased results.

To join, you must be aged between 18 and 70, have been taking Ozempic and had stable doses for at least 3 months, and meet certain health criteria. You cannot join if you have Type 1 Diabetes or certain other health issues.

  • Length: 52 weeks
  • Visits: Multiple check-ups required
  • Eligibility: Specific health criteria and current Ozempic use
Study details
    Type 2 Diabetes

NCT07502508

Biomea Fusion Inc.

25 April 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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