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STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)

Trial studying heart valve replacement for severe aortic stenosis symptoms.

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

The STAR Trial is studying a new way to help people with a heart problem called aortic stenosis. Aortic stenosis is when a valve in the heart becomes too narrow, making it hard for blood to flow. This study looks at a special treatment called **TAVR** (Transcatheter Aortic Valve Replacement), which replaces the old valve without major surgery. The Siegel™ TAVR System will be tested for safety and how well it works over time.

  • The study is for adults 18 years and older who need a new heart valve due to severe aortic stenosis.
  • Participants need to visit the doctor for follow-ups and understanding the procedures is necessary.
  • Some conditions like certain heart, blood vessel, or lung issues may prevent participation.

If you have this heart condition and meet the criteria, this study may help improve your condition without traditional surgery. However, it's important to understand all requirements and risks before participating.

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Study details
    Symptomatic Severe Native Aortic Stenosis
    Aortic Stenosis

NCT07278310

MiRus

11 April 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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