Atopic Dermatitis is a skin condition that causes itchy, red, and inflamed skin. This study is testing a new medicine called BFB759 to see if it helps people with moderate to severe atopic dermatitis. The study lasts about 36 to 40 weeks, and it's double-blind, meaning neither the participants nor the researchers know who is getting the real medicine or the placebo (a fake treatment that looks like the real one).

Adults between the ages of 18 and 75 who have had atopic dermatitis for at least a year and aren't getting better with creams or ointments can join the study. Participants must also attend regular doctor visits and follow instructions carefully.

Some people cannot join, like those with certain infections, those who are pregnant or breastfeeding, or those who have recently used other medicines that might affect the study.

• Study Duration: 36 to 40 weeks with regular visits.
• Participants must avoid certain medications during the study.
• People with specific health conditions are not eligible.