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A Phase II Study of HRS-4642 Combined With AG (Nab-paclitaxel and Gemcitabine) as Conversion Therapy for Locally Advanced Pancreatic Cancer

Study of Investigational Medication with AG Regimen for Locally Advanced Pancreatic Cancer

Recruiting
18-75 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates locally advanced pancreatic cancer. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication combined with the AG regimen as a conversion therapy.

The study focuses on assessing how well the investigational medication works and its safety. It evaluates different aspects like response rates and quality of life changes.

  • Who can participate: Adults aged 18 to 75 with locally advanced pancreatic cancer may participate. Key eligibility includes confirmed pancreatic ductal adenocarcinoma and no prior antitumor therapy.
  • Study details: Participants will receive the investigational medication combined with other treatments. A placebo is not used in this study.
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Study details
    Locally Advanced Pancreatic Cancer With KRAS G12D Mutation

NCT07438106

The First Affiliated Hospital with Nanjing Medical University

22 August 2026

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