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Neural Mechanisms and Clinical Applications of DBS for Modulating Sleep Dysregulation in PD

Exploring DBS effects on sleep in Parkinson's patients.

Recruiting
19-80 years
All
Phase N/A

Parkinson's disease (PD) is a brain disorder causing movement problems and sleep issues. This study looks at how a treatment called **Subthalamic Nucleus Deep Brain Stimulation (STN-DBS)** affects sleep in people with PD. DBS is a therapy that sends electrical signals to the brain to help with movement symptoms. Researchers believe it might also help with sleep, but they need to learn more about how it works. The study will use a **Polysomnography (PSG)** device, a tool worn to record sleep patterns, and **Local Field Potentials (LFPs)**, which are brain signals, to understand changes in sleep patterns with DBS therapy.

  • **Study Length:** Participation lasts over a year, with visits at 1, 3, 6, and 12 months.
  • **Compensation:** Not mentioned in the details provided.
  • **Risks:** Involves surgery and may not be suitable for those with severe illnesses or mental health issues.

To join, you must have PD, have had DBS surgery, and be willing to attend follow-ups. You cannot join if you've had other brain surgeries or have other serious health conditions.

Study details
    Deep Brain Stimulation
    Parkinson's Disease and Parkinsonism
    Sleep Disorder

NCT06914466

Xuanwu Hospital, Beijing

17 April 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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