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A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Exploring Xaluritamig plus abiraterone for advanced prostate cancer treatment.

Recruiting
18 years and older
Male
Phase 3

This study aims to see if a new treatment combination, Xaluritamig plus Abiraterone, helps patients with metastatic castration-resistant prostate cancer (mCRPC) live longer than current treatments like Docetaxel, Cabazitaxel, or Abiraterone. Metastatic means the cancer has spread from the original site, and castration-resistant means the cancer continues to grow even after treatments that lower testosterone.

To participate, you must be 18 or older, have prostate cancer that has spread, and have tried one other treatment without success. You cannot join if your cancer has spread to your brain or if you've had certain other treatments recently.

  • This study compares two treatment groups and requires prior consent.
  • Participants must have previously undergone specific treatments and procedures.
  • There are several exclusions based on prior treatments and current health status.

Be aware that this study involves specific eligibility requirements and previous treatments. Participants will be monitored for their health and response to the treatment. It's important to discuss with your doctor if this study is right for you.

Study details
    Metastatic Castration-resistant Prostate Cancer

NCT07213674

Amgen

11 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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