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Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

Phase 4 trial: Evaluating NT-501 safety for MacTel Type 2 patients.

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18 years and older
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Phase 4

This study looks at the long-term safety and effectiveness of a treatment called NT-501 for a rare eye condition called Macular Telangiectasia Type 2 (MacTel). It's a Phase 4 study, which means it's checking the treatment's safety over a longer time after earlier phases showed it works.

NT-501 is an implant placed in the eye. Some people in the study received this implant in earlier studies, while others had a pretend procedure (sham) and will now get the real implant. The study has three groups:

  • Group 1: People who got the implant in earlier Phase 3 studies.
  • Group 2: People who got the implant in Phase 1 or 2 studies.
  • Group 3: People who had the sham procedure and will now get the implant.

Key Points:

  • This study will follow participants for a long time to ensure the treatment is safe and works well.
  • Only Group 3 will have a new procedure to get the implant.
  • Participants must meet certain health conditions to join and agree to study rules.
Study details
    Macular Telangiectasia Type 2 (MacTel)

NCT06971939

Neurotech Pharmaceuticals

6 June 2026

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