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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

Study comparing treatments for EGFR-mutated lung cancer patients.

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)
Study Summary

This study aims to understand how well the drug osimertinib, with or without chemotherapy, works for people with a certain kind of lung cancer called EGFR-mutated Non-Small Cell Lung Cancer (NSCLC). The EGFR mutation involves changes in a gene that can make cancer cells grow faster.

Patients will not receive any new or experimental treatment; instead, researchers will observe those already receiving standard care. This means doctors will use routine treatments and note how patients respond. Up to 538 patients will join, and their progress will be tracked.

  • The study is observational, meaning no new treatments are given.
  • Doctors decide if osimertinib is used alone or with chemotherapy.
  • The study involves up to 538 participants, gathering routine data.

To join, patients must be adults with advanced NSCLC and a confirmed EGFR mutation. They should not be in any other cancer treatment trial. The study will help scientists learn more about the safety and effectiveness of these treatments.

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Study details
    Non Small Cell Lung Cancer
    Epidermal Growth Factor Receptor Gene Mutation
    Stage III Lung Cancer
    Stage IV Lung Cancer

NCT06538038

PrECOG, LLC.

25 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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