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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Comparing Soquelitinib and standard treatment for specific T-cell lymphomas.

Recruiting
18 years and older
All
Phase 3

This study compares a new drug called **soquelitinib** with standard treatments for certain types of blood cancer. The cancers being studied are forms of **T-cell lymphoma**, which is a cancer affecting white blood cells. The study is randomized, meaning participants are randomly assigned to receive either soquelitinib or a standard treatment chosen by their doctor. It is an open-label study, so both the doctors and patients know which treatment is being given.

Participants will be treated for up to two years, or until their cancer worsens or they can't tolerate the treatment. If the cancer progresses while on the standard treatment, participants might switch to soquelitinib.

  • **Duration:** The study can last up to 2 years.
  • **Participation:** Approximately 150 people will join, and they must be at least 18 years old.
  • **Risks:** As with any treatment, there could be side effects, and participants' health must be closely monitored.

Participants should have a life expectancy of more than 12 weeks and have previously tried 1 to 3 other treatments for their cancer.

Study details
    Peripheral T-Cell Lymphoma
    Not Otherwise Specified
    Angioimmunoblastic T-cell Lymphoma
    Follicular T-Cell Lymphoma
    Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
    Systemic Anaplastic Large Cell Lymphoma
    Lymphoma
    T-Cell
    Peripheral
    Lymphoma
    T-Cell

NCT06561048

Corvus Pharmaceuticals, Inc.

28 March 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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