This study is for people with Sickle Cell Disease (SCD) and looks at how a medicine called *Pociredir* moves through the body. **Pharmacokinetics** is a term that describes this process. Participants are divided into two groups: Fasted and Fed. The Fasted group won't eat for at least 10 hours before taking the medicine and 4 hours after. The Fed group, if included, will eat a high-fat breakfast 30 minutes before taking the medicine. **Key Points:** - You will stay in a clinic from Day -1 to Day 3 or Day 4, with a follow-up visit on Day 4 and an end-of-study visit between Days 8-11. - You must have lab tests and meet certain health criteria to join the study. - The study includes a screening period, inpatient stay, and outpatient visits, with blood samples taken up to 72 hours after dosing. Participants will be monitored closely and required to follow specific dietary instructions. Only those who meet all inclusion criteria and none of the exclusion criteria can join. This study helps researchers understand how *Pociredir* works in people with SCD.