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A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Exploring new bone marrow transplant options for blood cancer patients.

Recruiting
18-75 years
All
Phase 1/2

This study wants to see if it's safe to give patients with blood cancers like leukemia or lymphoma a bone marrow transplant from someone who has passed away. A bone marrow transplant is a procedure where new healthy cells are put into your body to help fight cancer. Before the transplant, patients will get special treatments to prepare their bodies, which can be strong (myeloablative) or gentler (reduced intensity). After the transplant, doctors will watch patients closely for 56 days to make sure they stay safe and keep checking on them for a year.

Key Points:
  • Participants will be observed for a total of one year.
  • Both men and women aged 18 to 75 years can join, depending on the treatment type.
  • Participants should not have a suitable living donor available for the transplant.
Study details
    Acute Leukemia
    Acute Lymphoblastic Leukemia
    Acute Myeloid Leukemia
    Acute Biphenotypic Leukemia
    Acute Undifferentiated Leukemia
    CLL (Chronic Lymphocytic Leukemia)
    Chronic Myeloid Leukemia (CML)
    MDS (Myelodysplastic Syndrome)
    Non-Hodgkin Lymphomas
    Hodgkins Lymphoma
    Cutaneous T Cell Lymphomas (CTCL)

NCT05589896

Ossium Health, Inc.

21 March 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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