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Pelacarsen Roll-over Extension Program

Join our Pelacarsen study for more ongoing research benefits.

Recruiting
18 years and older
All
Phase 3
Pelacarsen Roll-over Extension Program

This study is for people who have finished one of two earlier studies and want to continue taking a medicine called pelacarsen (TQJ230). Pelacarsen is a treatment given once a month to help people with high levels of a substance called Lp(a) and a heart condition known as ASCVD (Atherosclerotic Cardiovascular Disease).

In this new study, everyone knows they are getting the medicine, unlike in the previous studies where some didn't know if they received the medicine or a placebo. The aim is to see if the medicine is safe to use for a long time.

  • Participants must have completed the earlier study and agree to continue with this one.
  • If someone had to stop the medicine before due to bad reactions, they can't join this extension study.
  • Doctors will decide if any other health issues might make participating unsafe for someone.

It's important to talk to a doctor to understand the risks and benefits before joining. Participants will help researchers learn more about the long-term safety of pelacarsen.

Study details
    Atherosclerotic Cardiovascular Disease

NCT06875973

Novartis Pharmaceuticals

11 April 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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