Image

Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

Exploring MRM-3379 effects in men with Fragile X Syndrome.

Recruiting
13-45 years
Male
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is exploring a medicine called MRM-3379 for males with Fragile X Syndrome (FXS), a genetic condition that causes learning challenges and developmental delays. **Participants:** Males aged 13-45, weighing at least 30 kg (about 66 pounds), and with a body mass index (BMI) between 18-36. Diagnosis requires a specific genetic marker. **Study Design:** Participants aged 16-45 will be randomly assigned to receive either the medicine or a placebo (a sugar pill) without knowing which. Those aged 13-15 will receive the medicine openly (everyone knows). The study lasts 12 weeks, and participants need to swallow tablets or capsules. **Safety and Tolerability:** The study checks if the medicine is safe, how well it is tolerated, and if it helps with FXS symptoms.

  • Participation involves 12 weeks of taking medicine and attending regular study visits.
  • Eligible participants need a consistent caregiver to help with the study.
  • Participants must be able to swallow tablets and have no other serious medical conditions.
Print
Study details
    Fragile X Syndrome

NCT07209462

Mirum Pharmaceuticals, Inc.

20 June 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.