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Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Studying Povorcitinib for teens with moderate to severe skin condition.

Recruiting
12-17 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at how the drug povorcitinib works in teens with hidradenitis suppurativa (HS), a skin condition causing painful lumps. Participants will use povorcitinib for 54 weeks to check its safety and effectiveness. Pharmacokinetics means how the body processes the drug. To join, you need to be between 12 and 18 years old, weigh over 30 kg, and have had moderate to severe HS for at least 3 months. You should have tried other treatments without enough success.

  • Duration: 54 weeks.
  • Participants: Ages 12-18 with moderate to severe HS.
  • Risks: Pregnancy, certain medical histories, and lab values may exclude you.

If you have more than 20 fistulas (draining tunnels) or certain health issues, you might not qualify. Women who are pregnant or breastfeeding cannot participate. You must agree to use birth control and follow study rules. This study aims to help find better treatments for young people with HS.

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Study details
    Hidradenitis Suppurativa (HS)

NCT07213973

Incyte Corporation

7 March 2026

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