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Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

Testing new treatment for recurrent meningioma against standard care.

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for patients with meningioma, a type of brain tumor, that has come back after treatment. It compares a new drug, [177Lu]Lu-DOTATATE, to regular treatment options. Patients will be randomly chosen to receive either the new drug or standard care, but they can switch to the new drug if their tumor progresses while on standard care.

Meningioma is a tumor that forms on the brain's outer layer. An MRI is a special scan that uses magnets to take detailed pictures of organs inside your body. WHO grade 1-3 indicates the tumor's severity, with 1 being the least severe and 3 more aggressive.

  • The study is open to adults 18 and older with confirmed meningioma.
  • Participants will need regular MRI scans and possibly PET-CT imaging.
  • Patients should discuss with their doctor if they can avoid surgery or radiation during the study.

If you're interested, talk to your doctor to understand if this study is a good fit for you.

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Study details
    Intracranial Meningioma

NCT06955169

RTOG Foundation, Inc.

25 April 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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