Image

A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.

Study tests dapagliflozin and baxdrostat effects on kidney disease and hypertension.

Recruiting
18 years and older
All
Phase 2

This study investigates how two medications, *baxdrostat* and *dapagliflozin*, affect people with chronic kidney disease (CKD) and high blood pressure. CKD is when your kidneys don't work as well as they should. We'll compare these medicines to see if they help reduce albuminuria, which is too much protein in the urine, a sign that kidneys aren't working well. The study is double-blind, meaning neither participants nor researchers know who gets which treatment, and it happens in different places around the world.

Participants must be 18 or older and have certain health conditions. You might need to stop taking some medicines before starting. The main goal is to check how these medicines affect albuminuria.

  • The study is international and double-blind, ensuring unbiased results.
  • You must be 18+ and meet health criteria to join.
  • Participation requires stopping specific medications.
Study details
    Chronic Kidney Disease and Hypertension

NCT07222917

AstraZeneca

25 April 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.