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Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

Testing Suzetrigine for pain relief in diabetic neuropathy patients.

Recruiting
18-80 years
All
Phase 3
**Study Overview:** This study checks how well a medicine called Suzetrigine works to relieve pain from diabetic peripheral neuropathy (DPN). DPN is a nerve problem caused by diabetes, leading to pain, especially in the legs. The study also ensures the medicine is safe and can be tolerated by those who take it. **Eligibility Criteria:** Participants should weigh at least 45 kg and have a body mass index (BMI) between 18 and 40. They must have type 1 or type 2 diabetes, with an HbA1c level (a measure of blood sugar) of 9% or less. They should have had pain in both legs due to DPN for at least a year and a pain score between 4 and 9. Participants should not have missed more than 3 pain score recordings in the week before starting the study. Additionally, they should not have taken a medication called Journavx within 30 days before starting this study and shouldn't have other sensory issues not related to DPN. **Key Points:** - **Duration:** The study requires a commitment of time, but exact length and number of visits are not specified. - **Compensation:** Participants might receive compensation for their participation. - **Safety:** The study focuses on both the effectiveness and safety of the medication.

Consider your eligibility and willingness to participate based on these factors.

Study details
    Diabetic Peripheral Neuropathic Pain

NCT07231419

Vertex Pharmaceuticals Incorporated

11 April 2026

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