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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Join a study on Mavorixafor for chronic neutropenic disorders and infections.

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12 years and older
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Phase 3
A Study on Mavorixafor for Chronic Neutropenia Participants This study tests a drug, mavorixafor, for people with chronic neutropenia, a condition where the body doesn't have enough white blood cells called neutrophils, leading to frequent infections. The study checks if mavorixafor helps increase neutrophils and reduces infections. Participants can continue their usual treatments like antibiotics or other medicines while in the study. Key Points:
  • The study involves ongoing monitoring and may require visits for blood tests.
  • Participants must have had at least two serious infections in the past year.
  • People with secondary neutropenia, like those from infections or other diseases, cannot join.
Participants need stable treatment for at least four weeks before joining and throughout the study. Those with certain health conditions or on specific medications may not qualify. The goal is to find if mavorixafor can make life better for those with this challenging condition.
Study details
    Neutropenia

NCT06056297

X4 Pharmaceuticals

7 March 2026

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