The study is designed to help understand if a new medicine called iloperidone, given as a long-acting injection (LAI), works better than a placebo (a fake treatment) in stopping symptoms of schizophrenia from getting worse. Schizophrenia is a mental illness that affects how a person thinks, feels, and behaves. The study is looking for men and women aged 18 to 65 who have been diagnosed with schizophrenia and still need treatment.

Key points:

• The study involves regular appointments to receive the injection and monitor health.
• Participants will be randomly assigned to receive either iloperidone or placebo.
• Participation is voluntary, and risks will be explained before joining.

People can't join if they have another mental disorder that needs treatment more than schizophrenia, as per the DSM-5 (a guide doctors use to diagnose mental health conditions) in the last six months. If eligible, participants will have ongoing psychiatric support throughout the study.