**Study Overview**: This research is looking into a treatment for certain advanced or spreading cancers, called metastatic solid tumors. It's a **Phase II trial**, meaning it's testing how safe and effective the treatment is. The study will happen in multiple locations and is "open-label," so both doctors and participants know what treatment they're getting. The trial is in two parts, combining a drug called **DB-1311** with either **BNT327** or **DB-1305**.
**Who Can Join?**: Adults 18 and older with certain cancers like liver, cervical, skin, head and neck, ovarian, or lung cancer can join if they have a life expectancy of at least 3 months and meet other health criteria.
**Key Points**:
- The study will check if the drug combination is safe and helps treat the cancer.
- Participants must not have had certain treatments before and should have good organ function.
- The study is for those who can't have surgery or radiation to cure their cancer.
Before deciding to join, it's important to discuss with your doctor to understand potential benefits and risks.
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