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A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Join a study on Sofetabart Mipitecan for different ovarian cancer types.

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18 years and older
All
Phase 3

This study is testing a new medicine, **Sofetabart Mipitecan (Sofe-M)**, for women with ovarian, peritoneal, or fallopian tube cancer. It's in three parts: Part A is for those whose cancer didn't respond well to regular platinum chemotherapy, while Parts B and C are for those whose cancer did respond well. The aim is to see if Sofe-M works better than current treatments and to ensure it's safe.

**Platinum-based chemotherapy** is a common cancer treatment that uses platinum to kill cancer cells. **Platinum-resistant** means the cancer grows even after using this treatment. **Platinum-sensitive** means the cancer stayed controlled for at least six months after treatment.

  • **Study Duration:** Depends on how well you respond to the treatment.
  • **Participation Requirements:** You'll need to provide a sample of your tumor tissue and meet specific health criteria.
  • **Risks and Benefits:** The study aims to find a better treatment, but as with any medicine, there could be risks.
Study details
    Ovarian Neoplasms
    Fallopian Tube Neoplasms
    Peritoneal Neoplasms
    Neoplasm Metastasis

NCT07213804

Eli Lilly and Company

12 September 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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