Image

A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

Study testing APL 3007 with Syfovre for geographic atrophy patients.

Recruiting
60 years and older
All
Phase 2
**Study Summary** This study is testing a new treatment called APL-3007 combined with another treatment, Syfovre/Pegcetacoplan (APL-2), for people with a specific eye condition called Geographic Atrophy (GA), which is a part of Age-Related Macular Degeneration (AMD). This is a Phase 2 study, meaning researchers have already done some testing and are now checking how well the treatment works and how safe it is. Participants must be 60 years or older and have GA in at least one eye. They must also have received previous treatment with Syfovre for their condition. **Key Points:** - **Duration & Visits:** Participants will be part of a longer-term study, with multiple visits over time. - **Eligibility:** Must have GA due to AMD, be 60+, and meet other health criteria. - **Compensation:** Participants may receive compensation for their time and travel. If you have this eye condition and meet the criteria, you might consider joining to help research new treatments. Always discuss with your doctor before participating.
Study details
    Geographic Atrophy Secondary to Age-related Macular Degeneration

NCT07215390

Apellis Pharmaceuticals, Inc.

7 March 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.