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Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Join a clinical trial for challenging Type 2 Diabetes treatment.

Recruiting
18 years and older
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Phase 2

**CAPTAIN-T2D** is a study for people with type 2 diabetes and high cortisol levels. Cortisol is a hormone that can affect blood sugar levels. The study has two parts. **Part 1** is the screening, lasting 5 to 9 weeks, where you will undergo tests to check eligibility. **Part 2** is the treatment phase, lasting 24 weeks, where participants will be randomly given either a new drug, **clofutriben**, or a placebo (a pill with no medicine). A follow-up phone call happens 4 weeks after the trial ends.

*Three key points to know about the study:*

  • **Duration:** Part 2 lasts 24 weeks with a follow-up call.
  • **Treatment:** You'll receive either clofutriben or a placebo.
  • **Eligibility:** Must be over 18, have stable diabetes treatments, and meet certain health criteria.

Consider participating if you have stable diabetes treatments and are okay with the trial’s length. Exclusions include new diabetes diagnoses, unwillingness to follow the trial procedures, or certain health conditions like severe sleep apnea or liver issues. Participation may help improve diabetes management, but discuss risks and benefits with your doctor.

Study details
    Type 2 Diabetes
    Cortisol Excess

NCT07296484

Sparrow Pharmaceuticals

12 September 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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