This study checks how well a new kind of scan called quantitative oblique back-illumination microscopy (qOBM) works to help doctors find skin cancer. **qOBM** is a tool that uses red light to look at the skin without surgery. It's like taking a picture of your skin from the inside! In this study, people with skin spots (called lesions) will have the qOBM scan. If you have skin cancer, you might have more scans before, during, or after your usual cancer treatment.

Key Points:

• The study involves multiple visits for scans, possibly over a year.
• Participants must be 18 or older with skin lesions.
• Those who've had surgery or radiation on the lesion area cannot join.

If you join, you'll help doctors learn if this scan works better than other methods to find out if a lesion is cancerous or not. This study could help improve how quickly and easily doctors can diagnose skin cancer, but it involves several visits and scans.