This study is looking at two different treatments for people with colorectal cancer that can't be removed by surgery or has spread to other parts of the body. **Pumitamig** and **bevacizumab** are both medicines given with **chemotherapy** (a treatment that uses strong drugs to kill cancer cells). The study wants to see which combination works better and is safer. To join, you must not have had these treatments before, and your cancer needs to be a specific type that doesn't have certain genetic changes.

• Study Length and Visits: The study involves multiple visits and treatments over time.
• Eligibility: You must have a certain type of colorectal cancer and meet specific health criteria.
• Risks and Benefits: There are risks with taking new medicines, but this study could help find better treatments.

Participants should not have other active cancers or certain heart conditions. If you are interested, discuss with your doctor to see if this study is right for you.