Study Overview: This study is testing a new medicine called duvakitug for people who have a condition called Ulcerative Colitis (UC), which causes sores and swelling in the belly. The study is looking at how well the medicine works and if it's safe to use.

Study Length and Visits: The study can last up to 35 weeks. You might need to come to the study site up to 8 or 15 times, depending on how your body responds to the medicine.

Eligibility: To join, you should be between 18 and 80 years old (some younger people might join if they meet certain growth standards). You must have been diagnosed with UC at least 3 months ago, and you should have tried other treatments that didn’t work well for you.

• This is a Phase 3 study, meaning it is in the later stages of testing.
• It involves different sub-studies, each lasting 12 weeks.
• Some participants may be asked to continue with additional visits for further monitoring.