This study tests a medicine called AZD5148 to stop Clostridioides difficile (C. difficile) infections from coming back. C. difficile is a germ that can cause bad stomach problems like diarrhea. The study is for people 18 years and older.
About the study: 230 people will join and get either AZD5148 or a placebo (a fake treatment) by a shot in the muscle or a push into a vein. The study will have up to 9 visits, including 2 site visits for eligibility and dose administration, and up to 7 planned visits. Phone calls and an electronic diary will be part of the follow-up.
Key Points:
- The study involves up to 9 visits and regular follow-ups.
- Participants will receive either the medicine or a placebo.
- No diarrhea is needed on the day of treatment.
To join, you must not have certain other bowel diseases or have had specific surgeries. If you have had a fecal transplant or certain other treatments recently, you cannot join. You must weigh at least 40 kg (about 88 pounds).