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A Superiority Trial of Radiofrequency Ablation for Low Back Pain

Testing radiofrequency ablation for easing low back pain.

Recruiting
18 years and older
All
Phase N/A

Low back pain can be really painful and make it hard to do everyday activities. The ASTRAL Study is checking how well a special treatment called Lumbar Radiofrequency Ablation (LRFA) works for people with chronic low back pain. This study will compare three groups: two groups with different LRFA methods and one group with a pretend treatment. LRFA is a procedure that uses heat to stop nerve pain signals. It's important to know this study is looking at which method works best and if there's a real benefit over not using LRFA.

  • The study lasts for 12 months, and you might need to visit the clinic a few times.
  • There are no new MRIs or evaluations for cognitive issues as part of the study.
  • You must be willing to follow all study steps and sign a consent form.

To join, you must be 18 or older, have had low back pain for 3+ months, and tried other treatments like physical therapy. You can't join if your pain is mainly due to certain spine problems or if you've had LRFA before. Make sure you're available for the whole study duration and can understand and speak English.

Study details
    Chronic Low Back Pain (CLBP)

NCT07222462

University of Washington

7 March 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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