Image

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Assessing anticoagulant safety in adults with atrial fibrillation.

Recruiting
18 years and older
All
Phase 2

This study is for adults with a heart condition called atrial fibrillation, where the heart beats too fast and unevenly. The research is testing two new drugs, REGN7508 and REGN9933, to see if they can help prevent blood clots better than a common medicine called apixaban. Blood clots can cause strokes, so it's important to find effective treatments.

During the study, doctors will check how much of the drugs are in the blood, if they cause side effects, and if the body reacts by making antibodies that could make the drugs less effective.

  • The study involves regular check-ups to monitor health and drug effects.
  • Participants should be ready for blood tests to check drug levels and effects.
  • Some people may not qualify, like those with certain heart or kidney conditions.

If you're interested, you'll need to have a specific heart score (CHA2DS2-VA) and not have certain conditions like a recent stroke or severe kidney issues. This study helps understand if these new drugs are safe and effective for patients with atrial fibrillation.

Study details
    Atrial Fibrillation (AF)

NCT07175428

Regeneron Pharmaceuticals

25 April 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.