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Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

Exploring Daraxonrasib for RAS Mutated Lung Cancer Treatment.

Recruiting
18 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

Study of Daraxonrasib in Patients With RAS Mutated NSCLC

This study aims to test a new medicine called daraxonrasib against a standard treatment called docetaxel, for certain lung cancer patients. Lung cancer in this study is called NSCLC, which stands for Non-Small Cell Lung Cancer. The study is for people who have a special change in their genes called a RAS mutation. The goal is to see if daraxonrasib helps patients live longer or stops the cancer from growing longer than docetaxel.

  • **Participation Requirements:** Must be 18+ years old and have been treated for lung cancer before.
  • **Study Details:** This is a Phase 3 study, where patients will either get daraxonrasib or docetaxel, like flipping a coin to decide.
  • **Exclusions:** Cannot join if pregnant, breastfeeding, or if previously treated with similar drugs.
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Study details
    NSCLC (Non-small Cell Lung Cancer)
    Non-Small Cell Lung Cancer
    NSCLC
    NSCLC (Non-small Cell Lung Carcinoma)
    NSCLC (Advanced Non-small Cell Lung Cancer)

NCT06881784

Revolution Medicines, Inc.

7 March 2026

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