Vonoprazan is a medication being studied to see if it helps adults with EoE, which stands for *eosinophilic esophagitis*. EoE is a condition where a type of white blood cell (eosinophil) builds up in the esophagus causing swallowing problems. This study will compare vonoprazan to a placebo, which is a pill that doesn't contain any medicine, over 12 weeks to see how well it works. Participants must be 18 or older and have a specific level of eosinophils in their esophagus. They should not have certain other health conditions like Crohn's disease or use certain medications before the study.
Key Points:
- The study lasts up to 24 weeks with regular check-ups to monitor progress.
- Participants must not change their diet and should not be using certain medications before and during the study.
- There is a need for compliance with the study protocol, including diary entries and multiple visits.
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