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Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

Exploring rFVIIa for bleeding stroke in clinical trial, Part 2.

Recruiting
18-80 years
All
Phase 3
**Study Summary:** The **FASTEST Part 2 Trial** is looking at a treatment for a type of stroke called **intracerebral hemorrhage (ICH)**, where bleeding occurs inside the brain. This study is testing a drug called **recombinant Factor VIIa (rFVIIa)** to see if it can help stop the bleeding when given quickly after a stroke starts. They believe this treatment might help people recover better after 90 days. Participants will be chosen randomly to receive either rFVIIa or a placebo (a look-alike but inactive treatment), along with the best standard care. **Key Points:** - **Study Duration:** Approximately 3½ years, with follow-ups at 30, 90, and 180 days. - **Participation:** Up to 350 people from several countries; participants must get treatment within 120 minutes of stroke onset. - **Compensation:** Participants will not pay for the study medication. This study uses special emergency consent rules to start treatment as soon as possible. If you join, you will have a CT scan of your brain and follow-ups to see how your health progresses. Participants must be aged 18-80 and meet specific health criteria.
Study details
    Intracerebral Hemorrhage

NCT07227246

Joseph Broderick, MD

7 March 2026

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