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A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Exploring CHS-114 with Toripalimab for advanced solid tumors.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is exploring a new treatment option for people with advanced solid tumors. It combines an experimental drug, CHS-114, with another drug named toripalimab, and possibly other treatments. The goal is to check if this combination is safe and works well to treat these tumors. A solid tumor is a lump of cancer cells that can form in various parts of the body. This research is for people whose cancer has spread and who might not have other treatment choices left.

  • Participants must have certain specific types of cancer and meet other health criteria.
  • People in the study will need to provide samples of their tumors for testing.
  • Some prior treatments or health issues might prevent someone from joining this study.

Before considering joining, discuss your health history with your doctor to see if this study is a good fit for you. Participation could help advance cancer treatment options, but it involves regular check-ups and tests.

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Study details
    Metastatic Solid Tumor
    Advanced Solid Tumor

NCT06657144

Coherus Oncology, Inc.

7 March 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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