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A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

Exploring new treatments for obesity and type 2 diabetes.

Recruiting
18-75 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at how well two medicines, macupatide and eloralintide, help adults with obesity or overweight and type 2 diabetes lose weight. Type 2 diabetes is when your body can’t use insulin properly, and insulin is a hormone that helps control blood sugar. The study lasts about 48 weeks (almost a year).

Eligibility: Participants should have type 2 diabetes and meet certain conditions. For example, they should have a stable weight and be taking diabetes medicine or managing with diet and exercise. They should not have other types of diabetes or recent heart problems.

  • Study lasts about 48 weeks.
  • Participants must be adults with type 2 diabetes and stable weight.
  • No recent use of certain diabetes medicines or heart problems.
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Study details
    Obesity
    Overweight
    Diabetes Mellitus
    Type 2

NCT07215559

Eli Lilly and Company

7 March 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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