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A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications

Studying eptinezumab for migraines when other meds don't work well.

Recruiting
18-75 years
All
Phase 4

Eptinezumab Trial for Migraine Relief

This study is testing a medicine called eptinezumab to see if it helps people with migraines, especially those who haven't felt better using other anti-CGRP medicines. Anti-CGRP medications target a peptide (a small protein) linked to causing migraines. This trial is for people who have at least 8 migraine days a month and haven't responded well to other migraine treatments like monoclonal antibodies (mAb) or gepants.

Participants shouldn't have used certain migraine medicines too much before joining. It's also not for those who have tried more than one CGRP medicine without success or have had certain cancers in the past five years. Importantly, you can't join if you've tried eptinezumab before.

  • Trial Length: The study includes a screening visit and a baseline period.
  • Visits: Regular visits are needed to monitor health and response to treatment.
  • Risks: Possible side effects and exclusion for certain health conditions.
Study details
    Migraine

NCT06701526

H. Lundbeck A/S

7 March 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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