LAAOS-4 is a research study to see if a procedure called left atrial appendage occlusion can prevent strokes in people with atrial fibrillation (a condition where the heart beats irregularly). This procedure uses a catheter, which is a thin tube inserted into the body, to block a small part of the heart called the left atrial appendage. The study will include people who are already taking oral anticoagulants (medicines that help prevent blood clots) but still have a high risk of stroke. To join, participants must be 18 or older, have a history of atrial fibrillation, and be on anticoagulants for at least 90 days before starting the study.
- Study Length: Participants need to be on anticoagulants throughout the study.
- Eligibility: High stroke risk, age 18+, and current anticoagulant use.
- Risks: Must not have a history of certain heart procedures or thrombus in the heart.
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