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Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome

Exploring brain stimulation and imaging for Gulf War Syndrome treatment.

Recruiting
40-80 years
All
Phase N/A
This study focuses on Gulf War Syndrome, a condition causing headaches, joint pain, and muscle pain. Researchers are testing a treatment called cranial electrical stimulation (CES) using a device named **Alpha-Stim™**. This device sends small electrical currents to the brain to help reduce pain, anxiety, and insomnia without drugs. **Participants** will be Gulf War veterans aged 40-80. A **key part** of the study is brain imaging with MRI (magnetic resonance imaging) to understand how the brain changes with CES treatment. Participants will be randomly assigned to either real or sham (fake) CES treatment, and will use the device for 60 minutes each evening over **6 weeks**. The total commitment is **7 weeks**, including pre- and post-treatment assessments. Key Points: - **Duration:** 7 to 13 weeks depending on treatment response - **Visits:** Involves multiple MRI scans - **Compensation:** Available for participants Participants must have daily pain and meet specific health criteria to join. The study excludes those with certain medical conditions or incompatible devices. Consent will be obtained before joining. If interested, contact the research team for more details.
Study details
    Gulf War Syndrome

NCT07151248

Emory University

7 March 2026

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