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A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

Exploring Efgartigimod's effects in Primary Sjögren's Syndrome patients.

Recruiting
18 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

This study is testing a medicine called efgartigimod to see if it helps people with moderate-to-severe Primary Sjögren's Syndrome (pSjD), a disease where the immune system attacks glands that make moisture like saliva and tears. Participants will be divided into two groups: one group gets the real medicine, while the other gets a placebo (a fake treatment). Later, everyone gets the real medicine. The whole study lasts up to about 105 weeks, which is about 2 years.

Eligibility: You need to be at least 18 years old and have specific medical signs like Anti-Ro/SS-A antibodies, which are proteins in the blood. Certain conditions, like fibromyalgia not under control or recent use of certain medicines, might prevent you from joining.

  • Study duration is approximately 105 weeks.
  • Includes double-blind and open-label treatment phases.
  • Eligibility requires specific medical criteria.
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Study details
    Primary Sjogrens Disease

NCT06684847

argenx

11 April 2026

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