This study is testing a new medicine called **MK-8527** to see if it can help prevent HIV-1, which is a virus that attacks the immune system. Researchers want to find out if taking MK-8527 once a month is as good as or better than the usual medicine taken every day to stop HIV-1. They also want to check if it is safe and if people feel okay taking it.
- Participants must be HIV-negative and meet certain criteria, such as having had condomless receptive anal sex recently.
- Participants should not be allergic to study medicines or have certain health conditions like hepatitis B.
- The study involves taking medicine once a month, and participants should not have taken similar HIV prevention medicines before.
You have to weigh at least 35 kg to join. People who have had cancer in the last 5 years or who have taken some specific HIV prevention treatments can't join. This study does not allow people planning to donate eggs during the study.
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